1. A symbol for false religion as described in the Bible book Revelation who is represented as a fornicator who kills God's people. Turning to other gods is often described as or compared to adultery in the old testament and the ancient city of Babylon is where many pagan beliefs began, many are still believed today (astrology, fortune telling, etc).
2. A total whore.
1. God will one day destroy Babylon the Great.
2. She had two kids by two dads before she was 20, got married to another dude, and got divorced because he found out she was cheating on him with another girl's fiance. She is such a Babylon the Great!