Top definition
Best Friends made through the diagnosis of brain tumors. Brain Tumor Friends Forever!!
I met Nikki and Melissa thru the brain tumor association and it didn't take long for us to be BTFF.
by ChickenMuscles June 03, 2010
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The Urban Dictionary T-Shirt

Soft and offensive. Just like you.

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2
Mr. Johnson and I sometimes hang outside of class. He's my BTFF.
by Mr. Johnson's Daughter November 02, 2013
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Dirty Sanchez Plush

It does not matter how you do it. It's a Fecal Mustache.

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3
Be the fuckung friend.
btff Be the fucking friend
by porno fonen April 28, 2004
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Donkey Punch Plush

10" high plush doll.

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