Big Fat Friend. The larger less good-looking friend of the hot girl at the bar. She can sometimes cock block a guy who is trying to sleep with the hot girl. Best to combat this by deploying your wing man.
Sheila was looking so hot, I was really trying to get up in that; but her BFF kept getting in the way.
by Steve O June 16, 2006
Abreviation used to call an overweight person, big fat fucker
brian told me to block that bff
by Nick P. December 26, 2006
biggest fucking fruit
by Bevin and Kate October 17, 2006
Abbreviation for: Best Fucking Friend. The person to whom you are closest.
Dude, you're my bff! We get along so well.
by little man August 16, 2005
"Butt Fucking Fagotts"
BFF is self explanitory with the REAL definition above
by Mark Pucheu October 12, 2006
When applied to women, an annoying acronym meaning Best Friends Forever, but when applied to guys, has a slightly more condescending meaning, such as Butt-Fucking Fags, or Biggest Fucking Faeries, or --you get the idea
OMG, those fags are sooo BFF!
by Mr. Carrington June 23, 2006
a lie. there is no such thing as having a BFF because eventually you will just stab each other in the back one too many times and it will be over forever.
the person you think is your best friend. if you're lucky enough to think you have one at the moment.

someone who is not worth crying over but you always do anyway

Person1: My so-called BFF just stole my guy/girl and now shes/hes pissed at me for no reason!

Person2: welcome to my world
by na//me November 15, 2005

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