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45.
BFF
Best Female Friend. An acronym usually used by a male to signify a best mate who is a girl
This girl is playing mind games on me. I may have to call the BFF and see if she can decipher the meaning of this text message.
by CageFightingBlogger May 26, 2013
 
71.
BFF
"Best female friend"

Differs from BF, which means "boyfriend."
I'm throwing a bachelorette party for my bff next week.
by Astergirl August 15, 2005
 
72.
BFF
But Fuck Fantasy, or Best Friend Fucker
you are the coolest BFF ever!
by poo November 10, 2003
 
73.
BFF
Boy fucks free:
What whores say about a man they really like to fuck because they experience orgasm
O my god, he here comes! That bff he's so good.
by Renee June 23, 2004
 
74.
BFF
a BFF is a Big Fat Fagthe first F can b substitutated for other words.
A boy being a BFF to a group of girls can also be refered to has: being a man slave, being held by the balls, kissing ass, or being a chump fool.
Man, Max has become a BFF for all the girls from this town, and that other town; what a fool
by Awesome Andrew May 02, 2005
 
75.
BFF
a two-timing b**** who says she's ur best freind, but turns into a preppy flirt in Uggs who steals ur guy. someone who is not worth crying over, but you do anyway.
ex. someone you probably know
by BrokenSoul February 09, 2005
 
76.
Used to describe a member of the opposite sex (or the same sex) that is your current Best Fuck Fantasy.
Mmmmm, he is my B.F.F.
by Being Me November 26, 2007
 
77.
Best fucking friend
If she was not my B.F.F. I would hate her.
by boofuu November 02, 2003