Top Definition
A feeling of displeasure and/or disappointment--often occurring when waking up after a long night of drinking next to an unattractive person and thinking, "Awfuck, why did I do that!"
I had awfuck's disease this morning when I woke up next to that nasty guy I took home from the party last night.
by TMull April 05, 2006
4 Words related to Awfuck's disease

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