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1.
It's what you say when some crazy ass, epic, and/or ridiculous shit goes down; usually said by a random on-looker.

Variants of the word "Aw Shit Son" include:
Aw Bob Saget
Aw Dayumn Son
Aw Damn It
*little white boy beats up a straight up baller*
Random On-Looker: AW SHIT SON

*a dude gets 20 caps in his ass*
On looker: AW SHIT SONNNNN!!!! DAYUMNNNNNNNNNNNN
by samhigginsisasexybeast December 19, 2009
 
2.
From fine ass nigga Marlon Wayans who plays Shorty in Scary Movie
"I'm high as a mothafucka.Aw shit son!"
by Dezii Babii July 17, 2006