In EverQuest 2 this is an attack or spell that upon casting affects the entire area around the caster within a certain radius.
Apple of Enlightenment (an object in the video game Earthbound)
Age of Empires (Game series by Microsoft)
Area of Effect (self explanitory)
The real and true meaning of "aoe" is Angel Of Eternity, a nickname givin to the creator of the channel.
Other rumors include Age Of Empires, and Annihalate, Obliterate, Erraticate (what the archons of the game Starcraft say when clicked multiple times).
Meet me in aoe
Welcome to channel aoe.