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2.
The desire to marry a man or woman who is older than your grandparents.
Billy: "Dude, I just hooked up with some sweet ass, man."
Joe: "Ah yes, Grandma Knockers, eh? You really have a serious case of Anna Nicole Smith Syndrome, dude."
by Christine July 19, 2005
 
1.
Unable to resist the temptation of money. See Gold Digger

To put money $$$ over love and happiness. See Anna Nicole Smith.

Always working to make money and never having any time to live and be happy.

Anna Nicole Smith Syndrome is a serious condition which affects a lot of people who are unable to live full lives, because money over powers love at every turn. See Asians. In a sense Anna Nicole Smith Syndrome is only being able to make decisions that evolve around money and not the heart i.e. asking for proof of income on first date and financial references to cross check after date.

That patient will develop a serious condition that will psychologically push them away from love to try and find someone who is better able to accommodate them financially, even if it means living unhappy with someone who is obviously not compatible i.e. age gap, culture clashes, language barriers, nothing in common etc. See arranged marriages or Mail Order Brides or Russian Brides.

Patients may have developed a strong influence for a father or maternal influence to keep them protected. In a sense the patient may be suffering from being sheltered all their lives and never having the confidence to take risks for love.

Or the patient might be suffering Hollywood Slut Syndrome where they do not care who they step on, how they get there, as long as they get what they want!
"Are you kidding?" "Lei-Lei has Anna Nicole Smith Syndrome!" "She only dates men who are successful graduates who come from money!" "Well little does that asian-ho know that the men who are fucking her have Anna Nicole Smith Syndrome and only marry women who come from money."

Candy: Hi Glenn
Glenn: Hi Bitch
Candy: Did you hear?
Glenn: No... what?
Candy: Well as you know I'm not one to spred idol gossip in class.
Glenn: No Candy you usually spred something else during lunch break!
Candy: Grrr! Well anyway Rebab is said to be going into an arranged marriage!
Glenn: And to think... I didn't even think they could give her away. (laugh}
Candy: It sounds like both her parents are suffering from Anna Nicole Smith Syndrome.
Glenn: Well if I were her husband to be I would be asking for a refund on the wedding night!

In the 1997 movie, 'Washington Square', Catherine Sloper (Jennifer Jason Leigh) an average, awkward type of girl from a prominent wealthy family is persuaded by the very handsome, persuasively romantic Mr. Morris Townsend (Ben Chaplin) who is gossiped to be poor and gossipers say only interested in Catherine for her wealth to engage. It could be said that Mr. Townsend was suffering from Anna Nicole Smith Syndrome if indeed true? A very powerful and sad movie (have tissues handy), with a very surprising ending that shows how far some people will go who are suffering from Anna Nicole Smith Syndrome. But who has the syndrome? The father? The daughter? The aunt? Or Mr. Townsend?
by The Moody Poet August 26, 2006