Top Definition
A female under the influence of the sleep-aid Ambien. This state is generally characterized by unsteady walking, semi-coherent ramblings, and bizarre behaviors.
My girlfriend is an Ambienne. Last night she popped a pill, and next thing I know she's falling down the stairs mumbling about how if I truly loved, her I'd give her dog my extra kidney.
by Colin Kealey April 17, 2008

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