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1.
A National co-ed Service Fraternity based on leadership, friendship, and service.
Alpha Phi Omega - the Fraternity with chicks!
by Big 'Ern November 24, 2005
 
2.
A co-ed service fraternity founded on the principles of leadership, friendship, and service. Alpha Phi Omega is an organization that has come to be respected on any college campus lucky enough to have one. APO is mostly known for their service, however they are also known for their general kindness towards others. Alpha Phi Omega is full of wonderful people who want nothing more than to make the world a better place. There are 11 regions and 102 sections within Alpha Phi Omega.

It was founded at Lafayette College by Frank Reed Horton in 1925 to create a new "standard of manhood." Horton took the scout oath and the scout law from the Boy Scouts of America. Originally, women were not allowed to be involved in APO, however, in 1976, women were inducted into it and Alpha Phi Omega became co-ed.
Guy: Hey! Are you going to pledge for Alpha Phi Omega?!
Girl: I don't know... what is it?
Guy: It's this awesome coed service fraternity! You get to do a lot of service, hang out with great people, get leadership opportunities, and it looks great on a resume!
Girl: Okay! I'd love to! How do I sign up?!
by mostlylovinlife November 04, 2012
 
3.
One of the largest Co-ed service fraternities. Otherwise known as those who were rejected from the real greek system but still want friends and to do good for the community. Usually known as the GDI fraternity, with good hearted people that are yet displeasing to the eye.
Guy: dude who is that girl over there? and what are those letters?
Dude: thats jane, she's in Alpha Phi Omega.
Guy: so she does alot for the community, and shes super nice? its a shame she's not hotter.
by greekguy12345 March 24, 2013