Top Definition
A cocky, arrogant, honest, compassionate fictional doctor on the drama series Grey's Anatomy. He is married to Izzie Stevens (Katherine Heigl) and played by Justin Chambers.
Alex Karev loves Izzie Stevens.

Izzie Stevens loves Alex Karev.

Although at times, pompous and arrogant, Alex Karev shows a softer, more compassionate side, especially towards Izzie Stevens.
by LBertrand October 09, 2009

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