AD
All-Day.

I nickname given to Adrian Peterson of the Minnesota Vikings, because he'll run all over your team all day.
Did you see AD set the single game rushing record against the Chargers?
by TCT February 26, 2008

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a-d
Slang used by dealers selling very strong anti-depressants.
A-D is short for anti-depressants.
Originated in South-Florida, often sold in bottle-quantities (e.g. full prescription bottles of 25, 50, or 75)
A-D is also used when referring to anti-depressants among peers.
"Yo man you got any A-D's?"
"Yeah I just got refilled last Wednesday"
--OR--
"Hey dude what A-D are you on?"
"HydrOXYzine 75mg, what about you"
"Paroxetine 25mg"
by bathsaltz November 19, 2015

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Anno Domaini, Latin/American for 'the domain name decades' with A.D. marking the years after the 'birth' of the domain names (1985).

Anno Domaini Inc. is a internet company based in Delray Beach, Florida. It's main focus is selling various brandable, descriptive and significant domain names. Anno Domaini Inc. A Dollar, A Dream and ... A Domain name.
Domain names are formed by the rules and regulations (certain procedures to follow) of the Domain Name System (DNS). Any name registered in this DNS, A.D. 1985 is A Domain name.
by Dutchie66 August 17, 2013

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Alpha Dog. The shortened name of rapper Alpha Dog from the rap group the G.D.I.'s. OR the leader/protector of the pack, usually the biggest and meanest memeber of a group of people, quite often an asshole.
A.D.'s gonna beat the hell out of you when he finds out you sucker punched his boy last night
by Joey_Bag_Of_Donuts August 13, 2010

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Code word for adrenaline needle, used as a last resort for someone who thinks they are about to die from a heroin overdose. Something about adrenaline counteracts the heroin, sometimes saving the user.
"Shit, I need the A.D."
by prongstape December 19, 2005

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Attention Deficit, SQUIRREL. A person who has such a bad case of ADD, that everytime they see a squirrel they have to announce it and look at it for a few seconds before they can finish their sentence.
Boy 1: Sorry man I have such bad A.D.S

Boy 2: Aw man so do, SQUIRREL, I
by What,huh June 22, 2011

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AD
AD stands for After Death
This happened 65,000 AD
by iiSkyHighSkyla March 16, 2016

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