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The size of one's biceps in inches.
Person 1: Damn have you seen Randy's 22's!?
Person 2: Yeah but Kimmie says that they are 17's.
by Randizzle 22 October 18, 2008
A 22-ounce bottle of booze. Often Malt Liquor and Mike's Hard. Popular on College Campuses for their relative cheapness and availiability after 8pm.
Four North Militia cuts loose with 22s, biatch, that's what's up.
by PT Zado January 29, 2004