Top Definition
The 22 Fillmore is a cross-town San Francisco bus that hits all the spots - The Mission, Potrero, The Lower Haight, The Fillmore. Negros pile up on this bus and get all loud and hiyfee and call they play cousins on they cell-a-phones and aks pregnant teenagers what be there baby-name. Cholos and even some white folk up in Pac Heights have been known to get down on the 22. (Otherwise known as the double-deuce)
Waiter: I should just forget tips tonight; my section looks like the 22 Fillmore.
by RLp May 26, 2005

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