Top Definition
Those with genital herpes. This is a reference to the fact that 1 in 4 people has genital herpes.
Joe: I went on a date with Karyn last night.
Mark: Dude, she's in the 1 in 4 club!
Joe: I won't be dating her again!
by 2014_chiguy May 04, 2008
5 Words related to 1 in 4 club

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