An emoticon representing the elusive emotion of awesomeness. Not all people who are sexy, deserving-to-live beasts use ._., but all people who use ._. should have broad-shouldered bodyguards for bullet-shielding purposes around them at all times. When used with more immediate communicative intent, ._. portrays mild frustration, jadedness, or indignation. When a person uses ._. after almost every line, don't read too much into its meaning, and don't be jarred by an occasional .-.

An emoticon that indicates depression or helplessness.

An emoticon that most of the times is a synonym for Apathy

A smiley depicting sheepishness or belittled astonishment (hence the small eyes).

If epic was a face, ._. would be it.

._. could be used to replace any word in the English language.
It can be used as an insult, a compliment, a neutral comment, etc. The face has no nose because I'm stupid.

An emoticon expressing apathy or "you just lost me".

A symbol used by numerous secret societies to indicate an unknown message whose cryptic meaning has never come to light. All attempts to discover its true meaning have met mysterious and sudden ends.

Known users include: The mafia, Al Capone, the Freemasons, Spongebob Squarepants, and Elvis Presley.

Basically means, in emotospeak, "O....kay." "O_o" can be used also.