Generally refers to a very commonplace handgun cartridge first developed for the 1911A1 Colt Autopistol, available in FMJ and JHP. A rather bulky round with a weight of roughly 11 grams, the .45 ACP is seen as the ultimate manstopper by American shooters. Though it is a sub-sonic round that uses relatively low-pressure charge, its sheer size can deliver enough energy to very literally stop a man in his tracks. On the flip side however, it does not have a substantial amount of piercing power. Other .45 cartridges include the .45 LC (for Colt Revolvers), .45 GAP (Glock Auto Pistol), and the .45-60 high-powered revolver load.
by Anonymous August 10, 2003
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1: A .45 caliber Firearm, usually a handgun.

2: A song written by Shinedown, with arguable many meanings but most certainly not about a breakup. many believe the song is about conformity and the dangers and sorrow of our shallow society.
"Yo nigga i bust you with my .45"

"send away for a priceless gift, one not suttle, one not o nt he list..."
by Pumba December 18, 2004
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it is a type of gun refured to as the colt 45
by Double D May 13, 2003
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it iz the tipe of gun refured to a s the M-1911A1 .45 ACP, 45 Colt auto, the 1911, 45 auto, 45 automatic....da colt 45 be refuring to the .45 long colt, a revolverater round.
45 da gun a my choise an my iq.
by Double Duh July 11, 2003
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Code for Goodnight. Usually finished with 143 and 1433 (meaning I love you and I love you too).
First Person: it's getting late, I'm getting tired.
Second Person: I'm going to go to bed, 45143.

First Person: 451433
by protohype02 November 27, 2016
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Referring to Donald Trump. The Daily Show with Trevor Noah calls him 45. In South Africa, 4 - 5 is slang for penis, according to Trevor. Its better than saying his name.
45 did this to Mexico today....
by HipWaldorf January 28, 2017
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When you know his name is donald trump but you don't want to call him the president so he's the 45 president so he's #45
Hey did you hear how #45 might get taken put of office for something about Russia????
by KayKay21 February 25, 2017
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