Top Definition
.22
A common caliber of rim-fire weapons. This is often thought to be an ineffective caliber by people who cannot hit what they are aiming at. Used properly, it can be extremely fatal, especially with high-velocity ammunition.
The burglar died from a single shot to the head from a .22 pistol.
by BlastMaster May 16, 2003

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.22
A popular calibre of firearm that size for size, does some of the most damage of them all.
My Ruger 10-22 is a very dependable rifle.
by tradesman June 07, 2003

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.22
Pistol or Rifle using .22 bullets. Do to it's small size, it has no stopping power, but is obviously much more accurate. If used correctly, is an extremely lethal weapon.
That dumbass with the .50 shot 6 times at me and miss, so I just popped on .22 and he was down.
by A guy. April 03, 2005

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.22
A .22 pistol.
"So I bust out my .22 and started laying down crew."
by Diego August 31, 2003

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.22
a very small gun dont buck this shit unless its a remington cause you aint coppin' nothin'.
The fuck you think your doing pullin' a deuce deuce (.22) on me that shit is funny cause that might burn through my damn shirt if your lucky.
by Irish Whiskey Man 4280 March 12, 2003

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.22
a small gun that does little harm when the standard firing function is used, but does a good deal of damage if it is used to bludgeon someone's eye areas.
Whatever you do, just don't use the deuce deuce on me. You might dent my soda can.
by I Dance Jigs March 12, 2003

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.22
A small caliber hunting cartridge only capable of taking down small game. In a self-defense role, the .22LR cartridge has little stopping power and little stopping power. So, just because Ice Cube says it's cool, don't go out and buy one. The 9mm is the better choice in defending yourself. Although it at best is a crappy round for anything but rabbits, it can be used for maximum infection because if used wisely, a .22 will not leave an exit wound.
Wow, you're gonna use a .22 to knock the bank over? Even the bank teller will whoop your ass!
by Spiku June 24, 2004

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