look up any word, like sweetest day:
 
1.
The hardest gang in the Jefferson City,MO area. They be fuckin them bitches so hard that they kill or "assassinate" the muff. This gang ain't nuttin to fuck with if you find yourself in Missouri. The Muff Assassins are a sect of the bloods and participate in various crimes and substance abuse activities.They in particularly enjoy Meth, Beating Women, Mini-Kegs, and Natural Light.
I was in JC and got jumped by the Muff Assassins while trying to buy some meth from them. They then proceeded to throw shit at me and tell me I had "Perty Lips."
by Butters - Muff Assassin November 02, 2008