Top Definition
A mental illness in which the afflicted is compelled to respond to others' sentences by rearranging them in something similar to the following format:

"I wish I was/had/etc. 'x,' then I'd get ALL the ladies!"

This disease is often accompanied by the "That's what she said" Virus.

NOTE: Does not have to make sense; in fact, it usually doesn't.
Sam has "I Wish" Disease. He really starts to piss people off with it.

Josh: " mom had a heart attack."
Sam: "I wish I had a heart attack! Then I'd get ALL the ladies!"
by Gammasite November 26, 2007
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