A term used when somebody camps or stays unwanted in a location for a prolonged period of time.
Look at that pakistani in the street! He's about to set up shop!
by Chrisx2 January 6, 2007
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The act of preparing oneself for a session of sex with oneself (jerking off).
I forgot my backpack and when I ran back in to my apartment I caught my roommate setting up shop.
by jeff74033 April 15, 2008
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To be on one's game, prominent, sufficient, and orderly. Someone who sets up shop real well has to be that person at the cookout dat talks to everybody and get's their fucking number
From Barbershop, set shop

Jimmy: Let me tell you somethin... you will *never* own a Black

barbershop!
Isaac: I will if I want to.
Terri: If Tony Roma can make ribs better than Black people, Isaac can

own a Black barbershop...
Calvin: Wait a minute...”ribs better than Black people?"
Jimmy: Tony Roma boils his ribs! That is *not* authentic!
by me tgr[sklg May 4, 2011
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