A command given to someone who needs to get his or her shit together. In a sports context, often said to one whose head isn't in the game, or who is playing erratically. In social situations, said to someone who is acting really strange or being embarrassing.
Joe: "Shit, this bar is never this crowded on a Wednesday... what are all these girls doing here? Looks like we picked a good night to come out."
Dwight: "Damn, look at the tits on these girls over here."
Hot Girl: "I heard that, you fucking creep."
{Joe angrily pulls Dwight aside.}
Joe: {pointing his finger in Dwight's face} "Hey, look at me. You lock it up. Don't be a liability tonight."
Dwight: "Alright, alright. Honest mistake."
by Fitterer January 20, 2006
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A command given to someone who needs to get his or her shit together. In a sports context, often said to one whose head isnt in the game or is up their ass, or who is playing erratically. In social situations, said to someone who is acting really strange or being embarrassing.
David: "What the Fuck!", Everybody lets pick this shit up right fuckin now. Everybody finish the drill. Let Go!"
Torres: "Fuck this i wanna go home and eat" (torres drags his nutz half speed through the drill)
David: "Move your fuckin tits Torres"{David angrily pulls Torres aside.}
David: {Grabs Torres's helmet} "Hey, look at me! You lock it up right now! Don't be a fat fuck today finish the fuckin drill."
Torres: "Alright, alright."
(David walks back to the line)
Torres:(Torress wispers) "Fuckin pussy"
by Ashton White October 17, 2006
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when one tells their friend a secret, and said secret teller wants to keep it between those two. Secret teller tells secret reciever to "lock it up"
"Dude, remember that mary girl?"

"Yeah."

"I nailed her last nite. But hey... lock it up."
by Chris Alfrey December 4, 2006
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A slang term used when asking someone for a street race. Usually for money or some type of wager.
Fresh whip, you tryna lock it up with my evo? We are throwing $50's.

You wanna lock it up tonight at 8:00? Everyone will be there.

All these civics are trying to lock it up and they know they can't win.
by Gorlak375 February 20, 2013
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A phrase used when one has lost control or is showing crazy symptoms; whether that is just in a social situation or when dating someone.

If you can't stop talking about someone, lock it up!
If you are making a fool of yourself in public, lock it up!
Just generally, if you are sucking, LOCK IT UP!
"Omg, I know we went on one date, but I think he's the one"

Lock it up!
by Jb2013 November 15, 2013
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A command given to an annoying individual who won't stop talking, bitching, or rambling about something you don't want to hear about, or exposed to the public.
Sue: Did you hear what she said?
Sue: I'm gong to kill her!
Sue: Why would she say that?
Sue: Did you hear her say it?
Sue: Am i really getting fat?
Sue: What time did she say it?
Sue: Are you sure she knows we did it?

Ned: Enough already! LOCK IT UP!!!!
by mandamich3ll3 July 21, 2007
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The groundswell chant heard around the world relating to the 45th President of the United States.
As I stood in the rotunda, surrounded by an expanding ocean of angry Americans, I felt the words, “Lock him up!” come rolling out of my throat.
by Dr Bunnygirl May 22, 2019
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