1) to be severely messed up due to consumption of drugs (mainly pot unless otherwise specified); 2) to be in the act of or have the desire to perform a task (usually relating to drug consumption); 3) (as a noun) a state of being
When dealing with pot: "wow that last bowl crippled me to the belt"
When dealing with other drugs, the drug must be specifically mentioned: "last night was out of control, i was so crippled drunk that i fell down a flight of steps and then urinated myself"
"dude hurry up and cripple that joint so we can go inside and feast mcdonalds"
"there is no sense in even trying to talk to Ronnie, he has been crippling the beer bong all night and is too messed up to form coherent thoughts"
"look at Pedro, that last hit turned him into a cripple"