Seen most often in the gay community, slang for Party n' Play. Party refers to drug use- most often meth (tina, ice, crank) but sometimes ecstasy (E, XTC, Adam) cocaine (coke, blow, ski, snow), or poppers as well(though the latter is not generally considered a PnP item. Play refers to sex. PnP is considered a scene in itself- sex and drugs.
U into PnP?
Na, man, I don't touch that shit.