A deeply, deeply committed commitment (like superglue), based on the tedious and lengthy process of consuming said fruit. You must be FULLY aware of the commitment you are making as you pick up the fruit, as lack of sufficient commitment will result in treacherous wastefulness.
You're pre-med? That's such a grapefruit profession! SNAP!
That's a grapefruit marriage, you better be willing to stick with it alllll the way, through the bitterness and sweetness.