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2 definitions by skunk379

 
1.
big boys are an 80 mg oxycontin. they pale in comparison to the oldschool 160's, but just get 2 and clean your spoon an it'll be allright!!!!
"what do you mean you want $60 for one of those big boys, I got em from you last week $45!!!!
by skunk379 May 23, 2006
 
2.
a pill,(featured in the movie "drugstore cowboy") that is a synthetic pain releiver. Best put in your arm.
I went to the doctor to refill my dilaudid prescription,and he rejected me cause of the tracks on my arms, and legs, and toes, and neck and.........
by skunk379 May 23, 2006