First heard on the tv show The Game, Ugly Girl Syndrome is when a girl is so insecure that she will do ANYTHING to please her man.
Tasha: I just know youve been with so many different women. Beautiful ones, freaky ones.
Rick: Don't tell me you have ugly girl syndrome
Tasha: Oh my god, are you saying im ugly? Im hideous, im an animal, dont look at me Rick!
Rick: Tasha dont be crazy. Youre beautiful. Im just sayin, you actin like you got that syndrome when a girl insecure youll do anything to please your man.