A street phrase meaning if you're going to rob someone, kill them as well. usually said by the one being robbed as a show of pride because they'd rather be killed then embarrassed by being robbed.
Also an awesome Nas song.
Robber: "Give me your money!"
Victim: "Take it in blood, I'm not going to be embarrassed like this."
Nas: "Time is money when it comes to mine, take it in blood."