When you know too much. A break down of the word shows that it is a combination of the words "wise" and "able" meaning that one is now empowered by knowing some fact or truth.
origins: The "w" is easily mistaken for an "m" and the word appears to be "miserable" on first glance to many people. The creator is dislexic and often writes and reads words and letters backwards or upside down.
1)light-hearted but-for-real tone: Dang these cupcakes are good but I'm sure if I saw the calorie count I'd be wiserable. Pass me another one!
2) serious gloomy tone: He was cheating on her and when she found out she was really wiserable.