A 1, 000, 000 : 1 ratio, as observed by professor Frink, ie one person in a million will find a joke funny.
A reference to Dennis Miller's sometimes mystifying commentary on ESPN's Monday Night Football.
*Lisa reads Comic Book Guy's Shirt*
Lisa: C:, C:\Dos, C:\Dos\Run. Ha! Only one person in a million would find that funny.
Frink: Yes, we call that the Dennis Miller Ratio.