A frangina is another name for a 'vagina'. It is primarily related to a foul, venereal, STI infested specimen but can be used to describe a person who is being a dick
Boy 1: Oh my God, that guy is pissing me off.
Boy 2: Yeh, he's such a frangina
Girl 1: Oh my pussy
is so disgusting today
Girl 2: Have you got a frangina