Du'ob is a contraction of the two words dude and boob. Used as a term of affection towards saffic women.
mixmasta: Hangin out with lesbians kicks ass
mixmasta: Yeah dude so like i was hangin out with these two lesbian chicks and they were talking about mountain biking and getting with chicks. You can talk to them about cool shit and stare at their boobs and they're cool with it. They're like dudes but they got boobs.