This is a complicated disorder which can only effect nice white ladies, often in the educational or social justice fields of employment, or through church based organizations.
The most recognizable symptoms include having an earnest and idealistic eagerness to help the more marginalized members of a society, such as persons of color, or the homeless. This can manifest itself through things like bake sales and canned food drives, although occasionally, more touchstone examples (such as that of a teacher assuming the role of mentor and parent) can be observed.
Nice White Ladies (or, NWL's) know that they are just that, though believe wholeheartedly that not only do their contributions actually change the world significantly, but that they are somehow better than everyone else. There is more than a tinge of irony in this.
The male equivalent to Nice White Lady syndrome is the Savior Complex.
Bill: Hey, where'd you get them shoes?
Terry: The nice white lady at the church gave them to me.
Aisha: That teacher ain't so bad.
Tameka: Only cause she got Nice White Lady Syndrome.
Neurotic, over privileged, middle aged white lady, with a high sense of entitlement.
These women are very skinny, and have never, ever, heard the word "No" in their lives. As soon as they do, they are reduced to shaking neurosis, as that of a an over-and-inbred puppy-mill dog. In any confrontational situation, they become timid, and are likely to 'bite' out of irrational fear alone.
These women are from middle class backgrounds, sometimes upper class (though the upper crust are rarely seen interacting in common society).
Poodles are the bane of any customer service employee.
Jeff: What was her problem?
Sarah: I know! She is such a poodle!
Tom: Check out the pantsuit on that poodle.