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1 definition by jon Appleseed

 
1.
to fuck the shit out of somebody, then never talk to them again despite seeing them around a lot. Usualy occurs between upper and lower classmen in high school and college.
bro 1: jon derailed that chick at that party
bro 2: I know, shed in two of his classes to
Bro 1: awesome
by jon Appleseed July 29, 2008
3 25