Friends who are so good together that there is no other description word to use beside awesome. They have a bond like you wouldn't believe. Generally boy-girl friendships. May be a friends with benefits type situation, but not always. This is the kind of friendship that makes significant others get suspicious.
Person one: Jon and Natalie are totally awesomefriends.
Person two: Yeah, I hear they do all sorts of weird romantic shit together, but it's not really serious.