A name used to refer to the completely canon romantic relationship between Dean Winchester and the angel Castiel "Cas" on the CW documentary "Supernatural."
Dean: Well, Cas, not for nothing, but the last person who looked at me like that, I got laid.
Sam: …um, why don’t you, uh, go keep an eye on Adam?
(Cas walks out, Dean winks at him suggestively)
Fangirl1: Oh my god did you see the way Cas was looking at Dean.
Fangirl2: :Sigh: It sends me to my happy place.
Fangirl1: Destiel is so hot.