Josie McCoy from "Josie and the Pussycats".
She is the very DEFINITION of the word.
More accurately, it is the actor that portrays Josie, Rachael Leigh Cook, who is the "doe-eyed beauty". But it's this movie that accentuates her big brown eyes the most.
Rachael Leigh Cook is a doe-eyed beauty
Josie McCoy is a doe-eyed beauty