1 definition by cg2009

Top Definition
a drug that most people have a love/hate relationship with..it works quickly to calm inflammation and pain from things like asthma, colitis, arthritis and so forth, but it makes you CRAZY. you can't sleep, your face gets puffy, you have the appetite of a ravenous bear and you want to bite everyone's head off. You feel like you are coming out of your skin and yet you know you would rather live with the side effects than be sick but you hope you can get off of this stuff asap before the men in white coats come and get your ass.
"Don't mind her. she's all jacked up on prednisone".
"Damn, this prednisone is making me hungry !"
"I love my puffy prednisone face !!"
by cg2009 April 03, 2010

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