1. a friend who is being a bitch, used in a playful manner, because if you use it seriously...you seem like an dumb ass.
2. a person who is being extremely flirty while appearing to have unclean body parts.
Beth, you hooker shit! Stop embarrasing me, haha!
Ew, look at that hooker shit all over James. You can practically see the fumes coming out of her underwear.