A transliteration of the acronym FML meaning "Fuck my life". It is used in legitimate situations where ones life is truly fucked but has found its way into the everyday vocabularies of typical bros and hoes in imitation of fmylife.com (the bash.org of retards).
Pooja: DUDE my cell is soo old I cant even see the time and text at the same time! i thought it was 11:30.. EFEMEL LOLZZ!
Jay-Z: OH FUCK ME
Jay-Z: I FORGOT TO PICK UP MY 7 YEAR OLD DAUGHTER FROM SOCCER PRACTICE
Jay-Z: 7 HOURS AGO
Jay-Z: HOLY SHIT