1 definition by WiscoHype

Top Definition
To smoke an entire eighth of marijuana in one sitting, usually one blunt. If you're hood, you'll burn this 50 in an oowop. Also the title of a Nas track off his album, "The Lost Tapes."
"Yo, round up the homies.I just copped some o.g. Let's blaze a 50 and get straight stupid."

"Blaze a 50, sit back in the drop top Azure Bentley. Of course wit me, this chick who'd make Bobby divorce Whitney." - Nas
by WiscoHype May 10, 2009

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