Taking psilocybe mushrooms and MDMA (ecstacy) together. Actually regarded quite highly within the drug subculture. The effects rarely last longer than 8 hours. The effects of the MDMA lend a very upbeat feeling to the user, usually resulting in a positive mushroom trip. Because MDMA is a fairly "reliable" good high, but mushrooms aren't (there can be bad trips), the MDMA high helps to stabablize the mushroom trip.