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1 definition by The Fanboy

A sexual act mentioned in the movie "FanBoys" because the writers knew that people went to see the movie, they would would automatically go home and look up the word on urban dictionary or invent some perverse act involving their testicles and some poor girl.
"Where do your testicles end up when you do a Mississippi Handbag?"
by The Fanboy May 02, 2009