1 definition by T-Diddy from the City

Top Definition
An affliction that usually develops in males during their early twenties, preventing them from getting some. Virgins are particularly susceptible. Common symptoms include:

- nice, friendly personality
- lower than average self-confidence
- frequent high-fives with females
- socially awkward
- perpetually single
- has numerous friends that are girls
- often seen wearing plaids
- hugs women using the A-Frame technique
Dan suffers from nice guy syndrome.
by T-Diddy from the City May 25, 2007
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