Disgusting, icky, weird, often referring to something that is squelchy - imagine poking a vat of goo, and the sound you will make is similar to "squick".
"It felt all squicky and disgusting..."
"Ewww, that is so SQUICKY!"
Referring to somebody who is most aesthetically displeasing, ie. ugly.
That guy you hooked up with was such an ugger!
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