Phrase quoted by famous stand-up comedian Dane Cook in "ISolated INcident"
The equivalent to the male "Cock Block," in which a female accompaniment creates the imposibility of her female friend to "get lucky" with a possible male interest. Done so by intentionally saying something completely irrelevant and embarassing. Commonly takes place in social gatherings.
Jane: So what do you like to do for fun, Billy?
Billy: Well I like to...
Jane's Friend: Sorry to interupt! So, Jane, how's your AIDS?