1 definition by Russ Buckley

Top Definition
a condition relating to the excessive playing of the video game Madden NFL 200-whatever.

1. your hands are hurting excessivly because of overplaying.

2. you withdrawl from all your friends to play the game in your dark basement alone.
"Sorry I can't type. I've got Maddenitis."

"Hey, how about you call Chad to see if he wants to come to the movies with us?"
"Nah, he's got Maddenitis."
by Russ Buckley August 09, 2005
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