1 definition by RobKnowledge

Top Definition
The mixing of cocaine and heroin/morphine simultaneously. May also refer to mixing of stimualates such as amphetamines with other opiates or benzodiazapines. The mixing of stimulant and depressant is intended to "confuse" the heart and/or respiratory system.
Yo that stupid f*cker was speedballing all night. Dumb sonofabitch.
by RobKnowledge April 15, 2008
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