Upfucked: Similar to back-asswards, something that you realize is inevitably going to be fucked up by something completely beyond your control. Recognition that something will be "fucked up" before it is actually "fucked up".
John and his goons will upfuck this one for sure!
Clyde is a walking upfuck!
Jane could'nt upfuck unzipping her skirt!
With the re-election of Mayor Nagin, New Orleans is completely upfucked!