1 definition by NinjaProfessor

Top Definition
The state or condition of being tired of seeing a particular or overexposed meme.
"I'm getting meme fatigue from the "Keep Calm and Carry On" thing - it's making me want to lose control and break things."
#jumping the shark #meme #internet #social media #expiration date
by NinjaProfessor August 11, 2013
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